Laboratory Equipment Supporting Protein Development, Characterization, and Assay Readiness

Albrem Biopharma maintains an integrated laboratory platform to support custom protein expression, purification, analytical characterization, formulation support, and assay-ready reagent development.

Our equipment is not presented as a standalone inventory. It is part of the practical infrastructure behind Albrem’s protein development workflows, helping clients move from construct, sequence, or early candidate concept to purified material, analytical data, functional readouts, and development recommendations.

From expression screening and purification to plate-based assays, protein quality assessment, growth monitoring, and bioreactor-supported production, Albrem’s laboratory capabilities are designed to support decision-making during the early and translational stages of biologics and protein development.

Equipment Organized Around the Work Albrem Performs

Albrem’s equipment supports the core workflows required to develop, evaluate, and prepare custom proteins and assay-ready reagents. Instead of functioning as isolated instruments, these systems work together across expression, purification, characterization, screening, formulation support, and process monitoring.

Workflow Area What it Supports Representative Equipment
Protein Expression & ProductionExpression screening, culture support, bioreactor workflows, cell growth monitoring, production feasibility
  • Infors HT Incubator
  • Infors Labfors Bioreactors
  • Eppendorf 120 Bioreactor System
  • Thermo Heracell Vios 160i
  • Beckman Vi-CELL XR
Purification & ConcentrationCapture, polishing, buffer exchange, concentration, sample preparation, purification workflow development
  • AKTA Purification System
  • Repligen KrosFlo TFF
  • Biotage Isolera One
Analytical CharacterizationPurity assessment, chromatographic analysis, protein quality evaluation, concentration and stability-related readouts
  • Agilent 1260 HPLC System
  • Waters UPLC System
  • Wyatt Dawn III Plate Reader
  • Thermo Scientific Multiskan GO
Assay Development & ScreeningPlate-based assays, functional screening, fluorescence/absorbance/luminescence readouts, qPCR-supported workflows
  • Agilent BioTek Synergy Multimode Reader
  • Spectramax iD3 Plate Reader
  • BioRad CFX Opus 96
Cell Analysis & Workflow MonitoringCell counting, viability assessment, flow cytometry, growth profiling, microscopy support
  • Beckman CytoFLEX Cytometer
  • Beckman Vi-CELL XR
  • Enzyscreen Growth Profiler 960
  • Invitrogen EVOS M5000

Supporting the Full Protein Development Workflow

Albrem’s laboratory platform supports the steps that often determine whether an early protein candidate, reagent, construct, or engineered variant is ready to advance.

The equipment base helps Albrem evaluate practical questions such as:

Can the protein be expressed in a usable system?

Can sufficient material be generated for downstream work?

Can the protein be purified and concentrated without compromising quality?

Does the material show acceptable purity, stability, or functional performance?

Can the protein or reagent support the intended assay or application?

Is the candidate ready for additional development, optimization, or external regulated testing?

This workflow-focused approach allows Albrem to deliver more than material alone. Clients receive technical context, analytical support, and development guidance that can inform next-step decisions.

Expression, Culture, and Production Support

Albrem’s expression and production infrastructure supports early development workflows for custom proteins, difficult-to-express proteins, engineered variants, and assay-ready reagents.

These systems help Albrem evaluate expression feasibility, compare production conditions, monitor culture performance, and generate material for downstream purification, characterization, and functional testing.

Representative capabilities include:

Controlled culture and production workflows
Expression screening and condition comparison
Bioreactor-supported development work
Mammalian and microbial workflow support
Growth, viability, and culture performance monitoring
Material generation for purification and analytical testing

Purification, Concentration, and Sample Preparation

Protein development depends on more than expression. Once material is produced, it often needs to be purified, concentrated, exchanged into appropriate buffers, or prepared for analytical and functional evaluation.

Albrem’s purification and sample preparation equipment supports workflows that help convert expressed material into usable development-stage protein samples.

Representative capabilities include:

Protein capture and polishing workflows
Purification method development
Buffer exchange and concentration
Sample preparation for analytical characterization
Preparation of material for assay development or formulation support
Workflow troubleshooting for difficult or low-yield proteins

Analytical Characterization and Protein Quality Assessment

Albrem’s analytical characterization equipment supports the data layer behind its protein development work. These systems help evaluate protein quality, purity, concentration, stability-related behavior, and suitability for downstream use.

This is an important part of Albrem’s value proposition. The goal is not only to produce a protein, but to help clients understand whether that material is suitable for the intended research, assay, translational, or development purpose.

Representative capabilities include:

Chromatographic analysis
Purity and quality assessment
Concentration and quantitation support
Stability-related readouts
Plate-based analytical measurements
Support for candidate comparison and readiness recommendations

Assay Development, Screening, and Functional Readouts

For protein engineering, formulation support, and assay-ready reagent development, Albrem pairs production and purification with functional and analytical testing.

Plate readers, multimode detection systems, and qPCR-supported workflows help Albrem evaluate whether proteins and reagents perform in the context of their intended use.

Representative capabilities include:

Plate-based assay development support
Functional screening
Fluorescence, absorbance, and luminescence readouts
qPCR-supported workflows where applicable
Comparative testing of engineered variants
Reagent performance evaluation
Assay-readiness support for client programs

Mammalian Cell Analysis, Imaging, and Process Monitoring

Cell health, growth behavior, and process consistency are important parts of protein development. Albrem’s cell analysis and monitoring tools support workflows where culture performance, viability, imaging, and process-related measurements inform next-step decisions.

Representative capabilities include:

Cell counting and viability assessment
Flow cytometry-supported analysis
Growth profiling
Microscopy and imaging support
Culture monitoring
Development workflow troubleshooting

How Albrem’s Equipment Supports Its Core Services

1

Custom Protein Expression & Translational Development

Expression screening, culture support, production feasibility, purification, analytical characterization, and material generation for downstream testing

2

Difficult-to-Express Proteins

Multi-condition troubleshooting, expression rescue workflows, solubility and yield assessment, purification support, and analytical evaluation

3

Protein Engineering & Optimization

Variant screening, functional readouts, stability-related testing, developability snapshots, and comparative candidate assessment

4

Custom Formulation & Assay Support

Assay-ready reagent preparation, plate-based testing, functional validation, concentration and stability support, and analytical confirmation

A Practical Platform for Translational Protein Development

Albrem’s laboratory equipment supports a practical development model for early and translational protein programs. The goal is not simply to produce a protein or run an isolated assay. The goal is to help clients generate usable material, understand performance, compare options, identify risks, and make informed development decisions.

This integrated platform supports Albrem’s work across:

Custom protein expression

Difficult-to-express protein rescue

Protein purification and characterization

Protein engineering and optimization

Assay-ready reagent development

Formulation and stability support

Functional and analytical testing

For clients, this means Albrem can help bridge the gap between early discovery concepts and more development-ready protein materials, data packages, and technical recommendations.